SPI
Ferritina menor 75 o 75-100 Saturación Transferrina menor 20-25% IRON REPLACEMENT THERAPY. Iron supplementation should be prescribed if the serum ferritin level is less than 75 ng/mL, the transferrin saturation is less than 20% to 25%, or both. The recommended dose is 65 mg of elemental iron, twice a day 1 hour before a meal.17 Ferrous sulfate 325 mg, twice daily, is the most common form of oral iron used, although ferrous fumarate can also be used. This can be combined with 100 mg to 200 mg of vitamin C for better absorption.17-19 Gastrointestinal adverse effects from oral iron include nausea and constipation. Oral iron may help mild RLS symptoms but may not be effective for severe RLS. If oral iron is not tolerated or effective, IV iron can be considered. Low- molecular-weight iron dextran is recommended due to the low risk of anaphylaxis.17,19,20 Symptom improvement with IV iron can occur after 2 to 4 weeks but could take up to 6 weeks.17,19 Of the low-molecular-weight IV iron formu...